Local, Regional, Dedicated, Flatbed, OTR & Owner Operator positions
Missouri is a central hub for trucking in the Midwest. Drivers can take OTR, Regional, Dedicated, or Flatbed routes with competitive pay, modern equipment, and predictable schedules. Major cities include St. Louis, Kansas City, Springfield, and Columbia. Expand your opportunities in nearby states: Arkansas and Illinois.
High pay, flexible schedules, and modern fleets make Missouri CDL-A jobs attractive. HazMat, Reefer, and Flatbed positions are in demand statewide, offering both new and experienced drivers opportunities to grow their careers.
Whether you are an owner operator or a company driver, Missouri provides diverse routes and benefits to maximize earnings and career growth.
Pay: $1,700–$2,100/week. HazMat & refrigerated freight, mostly no-touch
Route: Long-haul OTR HazMat & Reefer
Home Time: 2–3 weeks out, 2–3 days home
Pay: Weekly pay: $1,450–$1,600. OTR routes last 3–7 days with predictable weekly home time
Route: Dedicated East or West Coast
Home Time: Weekly | 100% no-touch freight
Pay: Weekly pay: $1,600 – $1,950. OTR lanes across Midwest, South, and Northeast
Route: OTR refrigerated freight
Home Time: ~1 day per week on the road
Pay: $1,400–$2,100/week. Mostly no-touch flatbed loads including steel, building materials, and machinery
Route: Regional flatbed lanes
Pay: $2,400–$2,600/week. Structured schedule with dispatch coordination for predictable miles
Route: OTR Dedicated HazMat freight
Weekly pay: $1,200 – $1,700. 100% Dry Van, automatic Freightliner Cascadia, flexible home time options, and bonus pay
Route: OTR routes across Midwest & East Coast
Weekly pay: $1,440 - $1,540. $5,000 sign-on bonus (paid quarterly)
Route: OTR: multi-day trips with home weekly
Weekly pay: $1,663–$1,700. Regional routes with 2–3 days at home per week
Route: Based in Saint Louis, Missouri, serving the Midsouth region
Weekly pay: $1,450–$1,550. $5,000 sign-on bonus. Home Weekly, No-Touch Freight
Route: Cross-country OTR freight across 47 states (excluding CA)
Missouri offers competitive pay, modern fleets, and bonuses for CDL-A drivers. Regional, OTR, HazMat, Reefer, and Flatbed jobs are available statewide with leading carriers. Major cities like St. Louis, Kansas City, and Springfield serve as hubs for multiple lanes and freight types.
Owner operators can grow their earnings through top carrier contracts. Missouri CDL-A jobs prioritize safety, compliance, and driver satisfaction, providing stability and growth for both new and experienced drivers.
Whether starting your CDL-A career or seeking new opportunities, Missouri provides dedicated, regional, and OTR positions helping drivers maximize earnings and career development.
"Missouri CDL-A jobs offer great OTR routes and competitive pay. I love the Midwest highways!" — James T., St. Louis
"Dedicated routes in Kansas City are predictable and the home time is excellent." — Rebecca L., Kansas City
"Flatbed positions around Springfield are steady and the freight variety keeps it interesting." — Michael R., Springfield
"Owner Operator roles in Missouri let me maximize earnings with high-volume lanes." — Linda S., Columbia
"HazMat runs from Jefferson City pay well and dispatch is very supportive." — Kevin M., Jefferson City
"I appreciate the mix of OTR and regional routes available. It fits my schedule perfectly." — Ashley P., St. Louis
"Dedicated CDL-A jobs give me weekly home time and steady pay—highly recommended!" — Tom H., Kansas City
"Flatbed work is organized, and I get good bonuses for safe driving." — Emily W., Springfield
"Missouri's central location makes long-haul OTR efficient, and fuel surcharges help with earnings." — Chris D., Columbia
"Applying for CDL-A positions here was easy, and the onboarding process is smooth." — Jennifer K., Jefferson City
Missouri’s central location in the Midwest, extensive interstate network, and diverse industrial base support a steady demand for CDL‑A drivers. Major highways such as I‑70, I‑44, I‑55, and I‑35 connect key freight corridors, distribution centers, and agricultural hubs, making the state an integral part of regional and long‑haul trucking networks.
Several sectors in Missouri contribute to strong employment opportunities for CDL‑A drivers:
Salary ranges vary by route type, experience, and carrier size. Approximate annual averages are:
St. Louis is a major logistics hub with extensive freight activity, intermodal operations, and access to the Mississippi River.
Average CDL‑A Salary: $58,000 – $74,000 annually.
Kansas City’s strategic location and freight infrastructure support strong demand for regional and OTR drivers.
Average CDL‑A Salary: $59,000 – $75,000 annually.
Southwest Missouri provides regional freight and connections to Oklahoma and Arkansas markets.
Average CDL‑A Salary: $54,000 – $67,000 annually.
Central Missouri offers steady regional routes with easy interstate access.
Average CDL‑A Salary: $52,000 – $65,000 annually.
Rural northern Missouri counties provide consistent regional work with lower living costs.
Average CDL‑A Salary: $50,000 – $60,000 annually.
Missouri’s strategic location between Midwest freight corridors, combined with a diverse economy and steady logistics demand, makes it a solid choice for CDL‑A drivers seeking competitive opportunities. Urban hubs provide frequent openings, while rural areas offer cost‑effective living and regional routes.
From St. Louis and Kansas City to rural freight lanes, Missouri offers CDL‑A drivers varied job options, competitive pay, and potential for long‑term career growth.
Explore top CDL‑A job opportunities across Missouri, with competitive pay, trusted carriers, and flexible routes.
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